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music

The Dead Science at Neumo’s

Tonight’s concert marks the final night of the Dead Science’s weeklong Festival of Culture to celebrate their new album, Villainaire. A week sounds like an excessive party, but it’s appropriate for the album’s treatises on decadent excess (and time and morality and the Wu-Tang Clan). Conceptual stunts aside, the Dead Science are at the height of their musical superpowers on Villainaire, and their live show is bound to be a spectacle of sophisticated rock bombast and avant jazz prowess. With allies Past Lives and Talbot Tagora. (Neumo’s, 925 E Pike St, 709-9467. 8 pm, $7, all ages.)

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‘I Served the King of England’

Just in time to commemorate the 40th anniversary of the Prague Spring comes this charming adaptation of the charming 1971 novel by Bohumil Hrabal, one of the great writers (along with Kundera, Havel, and Skvorecky) of that hopeful, doomed era. I Served the King is a gallows- humor comedy about a young man who just wants to own a fancy hotel and make sweet, sweet love to pretty young ladies. He is constantly battered by the forces of Czech history—Nazis, Communists—but never loses his light, scheming spirit. (See movie times, www .thestranger.com, for details.)

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NASCAR-CUP: Richmond Int’l Raceway traffic alert

See trade alert: sunday, september 7 at richmond international raceway richmond, va (september 6, 2008)-guests attending the emerson radio 250 nascar nationwide series family on sunday, september 7, scheduled for 7:00 p.m., are encouraged to arrive at richmond international raceway no later than 4:00 p.m., proper to the egress of traffic following the 1:00 p.m. start of the chevy shock & roll 400 nascar sprint cup series tribe. railroad officials, working with henrico county police, are anticipating a heavy egress of traffic following the chevy rock & roll 400, which …

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Radio Milks Cows, Runs Street Cars (Feb, 1931)

Radio Milks Cows, Runs Street Cars

THERE seems to be no end to the versatility of radio in these days of electrical and mechanical miraclesnot even cows and street cars are immune to the influences of its radiations. As a curtain raiser at the annual radio show held recently in St. Louis, a street car was operated from a distance by a mere man with a radio transmitter in his hand, and a Holstein cow was made to dispense her milk by the medium of radio waves, whether she liked it or not.The mechanism of the trolley car and the mechanism of the milking machine were hooked up to a specially constructed radio receiver using only a five-foot length of copper pipe as an antenna. At a distance stood the operator, holding a portable radio transmitter using a similar antenna, as shown in the accompanying photos. When the key was pressed at the transmitter, the distant receiver in both cases set the machines to operating.


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Is That iPhone In Your Pocket Just Location-Based Ad Bait?

Eventful_slogan With the iPhone’s new app store making it easier for third parties to tap into the phone’s GPS capabilities, it was only a matter of time before advertisers jumped on board.

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Today, online event tracker Eventful announced plans to work with geotargeting ad network 1020 Placecast to send targeted, location-based ads to its users.

Eventful is an online event tracker that keeps users abreast of upcoming local shows and gatherings and facilitates the ticket buying process. Placecast is Eventful’s first cross-platform partner. As such they will serve advertisements to Eventful’s webpages and mobile site including their iPhone application that went live in August.

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Eventful’s iPhone app locates the user and informs them of events happening nearby. Now Placecast can use the technology to send localized advertising to Eventful users.

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Placecast will also be sending tailored advertising to users according to zip code searches and other entered data, but it’s the mobile aspect that presents the most potential for advertisers.

Stranded smartphone users are a strangely captive audience. Ads that would go unnoticed online local restaurants or hardware stores are exponentially more useful to a person looking for food or a hammer while standing on a street corner.

Currently, it looks like Eventful is still beholden to the advertisers that Placecast has signed on. The two advertising examples in the press release were for car dealerships near concerts that users would be interested in. The chance of a Coldplay fan being in the market for a new Scion just outside the concert venue is slim, but it does speak to the possibilities for relevant, location-based advertising in the future.

When advertisers figure out the details, they could score a windfall in mobile by minimizing the intrusion and providing people with something they actually want useful information.


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Fipresci hands prize to ‘Blood’

international news: anderson to receive prize in san sebastian — paul thomas anderson’s searing portrait of overweening goal, “there will be blood,” has won the fipresci (the intl. federation of film critics) grand prix benefit of film of the year.

P. Diddy Slams John McCain: “There Aren’t Any Black People In Alaska”

diddy is not amused with john mccain’s vice presidential running mate, sarah palin. diddy slams mccain on his latest video blog for be undependable with this decidedness to make a note the chick from alaska up in the mix. after introducing himself by his “regulation name” sean combs he goes on reasonably and rationally (not) to describe …

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CPS#76, Part 2

part 2 of this week’s sketch designs:

leave a bring up the rearoriginator - laura williamssupplies:patterned cardstock - my mind’s glad eyestamp - uniformity stamp companyink - close to my heartrub-ons - kaiser craftsbuttons - ingenuity supply

always on my minddesigner: debbie olsonsupplies:stamps: always, stitched by stampin’ upcardstock: soft sky, chocolate chip, very vanilla (su)ink: soft sky, versafine vintage sepiamarkers: chocolate chip, certainly celeryaccessories: muffle wild blue yonder stitched grosgrain; adhesive-backed pearlstools: spellbinders labels 2 die, martha stewart crafts scalloped cord fringe punch

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Online Ad Spend Tied To Olympics Expected To Reach $100 Million: Lehman

Of the $1.5 billion that marketers are expected to spend on advertising tied to the summer Olympic games, only $100 million will go towards online, said Lehman Brothters internet analyst Doug Anmuth during a conference call the investment bank hosted. Naturally, NBC and its marketing partner Microsoft (NSDQ: MSFT), stand to benefit the most from the related digital ad spend. But Anmuth expects Yahoo (NSDQ: YHOO) and AOL (NYSE: TWX) to leverage interest in the games, which kicks off in Beijing on Friday, for their sites and should also see some ad dollars heading their way as well. To a lesser extent, Google (NSDQ: GOOG) should benefit somewhat from search activity and from the Olympics highlights that YouTube will be showing as well.

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The shift to digital: A large part of the Olympics’ revenue will be incremental, said Art Ventura, SVP, ad sales, for Cablevision’s (NYSE: CVC) MSG Media. He and Brad Adgate, SVP, research for Horizon Media, noted the weak ad economy will surely have some impact. And so, NBC has to price aggressively, therefore each unit is producing less revenue than it might have been expected. Secondly, because of the panoply of choices from cable to digital, the ad market surrounding the Olympics is not that tight anymore, even in the midst of a presidential campaign.

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Sports’ strength: Art Ventura, SVP, ad sales, for Cablevision’s MSG Media: “Obviously, the economy is a question mark for everybody. But sports doesn’t have much a of DVR issue around it; people want to watch it as soon as they can, not later. Olympics is still a safe harbor for ad dollars, as are most sports.”


Digital packages: How will other online outlets affect NBC’s take? Mike Shields, Mediaweek’s senior editor, digital, said he doesn’t think the NBC will have to worry about competition from other sites taking away audience from NBCOlympics.com. For example, YouTube will only have about three hours a night, while MSN will direct users back to NBC’s website. He did say he was surprised that the network didn’t go after long-tail sports for the website or that it tended to avoid internet-only advertisers.

Sponsors drive ad spend: In a report that accompanied the call, Lehman compared past ad sales levels and concluded that official sponsors of the Olympic Games are buying roughly 50 percent of the available ad inventory both on television and online. Telecom, soft drinks, corporate imaging and movies are showing strong interest. Retail advertisers supporting “back-to-school”campaigns are also performing well.

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Stark & Stark - New York Injury Lawyer - Hudson County Business Attorneys … Robert J. Durst II is Chair of the Divorce Group of Stark & Stark. He limits his practice to …

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Apr 24, 2008 Getting back to the music, if you had something smaller like a Sandisk Sansa c250 MP3 player, this might not have been a problem.

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Tapping Tobacco to Cure Cancer

Sure, broccoli fights cancer. But tobacco?

When scientists at Stanford University looked around for a good way to grow a cancer vaccine, they realized they could do no better than the plant that has caused more cancers than you can count. They were not trying to develop a cancer vaccine such as Gardasil, which gives the body immunity against an infectious agent (in this case, the papillomavirus) that can trigger cancer (in this case, cervical). That’s all well and good, but the true grail is a therapeutic vaccine, one that would prompt the body’s immune system to attack cancer cells and only cancer cells, or that would consist of antibodies that do so.

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The theory rests on the fact that the surface of malignant cells are studded with molecules that can prime the immune system’s T cells, for instance, to attack the cancer cells, or act as homing signals that lure antibodies to munch up and destroy the cells.

A bunch of such cancer vaccines are in development, but they face a serious problem. Everyone is likely to need a different vaccine, because everyone’s cancer cells are probably slightly different on the molecular level. Growing the antibodies according to the usual recipe means using animal cells, which is expensive (thousands of dollars per patient), time consuming (months) and possibly risky (they might contain viruses or other contaminants that are not exactly what you want to inject into cancer patients). So biologist Ronald Levy of Stanford University and colleagues decided to investigate plants as vaccine factories.


This evening, they are announcing in the advance online issue of the Proceedings of the National Academy of Sciences that they have grown an injectable cancer vaccine in genetically-engineered plants, tested it in 16 cancer patients and found it to be safe (tests of whether it works come next).

Fully aware of the irony here, Levy and his team used tobacco plants to grow the vaccine, which would act against follicular B-cell lymphoma. This chronic, incurable form of non-Hodgkin’s lymphoma strikes some 16,000 people in the United States each year. For all its horrors, however, follicular B-cell lymphoma just may be tailor-made for a cancer vaccine: all of the malignant cells are the descendants of a single bad actor and have an identical molecule on their surface. But the molecular signature of one patient’s cancer cells is slightly different from every other patient’s; hence the need for potentially expensive personalized vaccines.

The scientists therefore spliced the DNA for the molecular sequences of the antibodies from each of the 16 patients into tobacco cells. The DNA triggered production of antibodies in the tobacco plants’ leaves which were tailor-made for each patient’s lymphoma cells. The scientists ground up the leaves and isolated the antibodies, injecting them into each patient.

The patients’ immune systems got cracking: 70 percent of the patients developed an immune response to the plant-produced vaccine, and 47 percent produced a response specific to the antigen.

it remains to be seen, of course, whether this will fight cancer. but growing cancer vaccines in plants has song big thing going for the sake it: patients would have a tailor-made vaccine within days, rather than waiting the months it takes to grow vaccines in savage cells.

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